目錄
Experiment 1 Preparation of Aspirin 1
Introduction 1
Experiment 2 Preparation of Paracetamo l8
Introduction8
Experiment 3 Preparation of Benorylate 13
Introduction13
Experiment 4 Preparation of Chlorobutanolum 18
Introduction18
Experiment 5 Preparation of Nikethamide 20
Introduction20
Experiment 6 Stability Study of Procaine Hydrochloride 24
Introduction24
Experiment 7 Preparation of Biphenyl Ketobutyric Acid 28
Introduction28
Experiment 8 Simple Distillation 33
Experiment 9 Melting Point Determination 35
Experiment 10 Recristallization 39
Experiment 11 Determination of Optical Rotation 42
the Laboratoty Report of Medicinal Chemistry 47
實驗一 阿司匹林的制備 49
實驗二 撲熱息痛的制備 52
實驗三 苯樂來的制備 54
實驗四 三氯叔丁醇的制備 57
實驗五 尼克剎米的制備 59
實驗六 鹽酸普魯卡因的穩(wěn)定性 61
實驗七 聯(lián)苯丁酮酸的制備 63
實驗八 簡單蒸餾 65
實驗九 熔點測定 68
實驗十 重結(jié)晶 70
實驗十一 旋光度的測定 74
實驗報告格式 78
Annex(附錄) 79